Seasons and episodes
1
Season 1 September 18, 2006
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1 - 1Will Ferrell, Jenny McCarthy September 18, 2006 -
1 - 2Eva Mendes, "So You Think You Can Dance", Granny Basketball September 19, 2006
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1 - 3Lisa Kudrow, 10 year-old Opera Singer, Adam Rodriguez September 20, 2006
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1 - 4Carol Burnett, Rainn Wilson, Hollerin' Championships September 21, 2006
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1 - 5Felicity Huffman, 'Animal Guys' Paul Hahn and David Riherd, Enrique Murciano September 22, 2006
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1 - 6Julia Louis-Dreyfus, Illusionist Criss Angel, Mario Lopez September 25, 2006
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1 - 7Debra Messing, Fashion Makeover with Lucky Magazine, Omar Epps September 26, 2006
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1 - 8
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1 - 9Sela Ward, Chris Noth September 28, 2006
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1 - 10Patricia Heaton, Duane Martin, Jesse McCartney September 29, 2006
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1 - 11Jane Kaczmarek, Masi Oka, Champion Cloggers October 02, 2006
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1 - 12Tom Bergeron, Eric Stromer, Elizabeth Perkins October 03, 2006
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1 - 13Tim Daly, Domino Magazine October 04, 2006
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1 - 14Connie Britton, Michael Clark Duncan October 05, 2006
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1 - 15Jennifer Love Hewiitt, Jonny Lee Miller, J. Xavier October 06, 2006
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1 - 16Virginia Madsen, Noah Gray-Cabey, Around The Office October 09, 2006
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1 - 17Marcia Cross, Clinton Kelly, Isaiah Washington October 10, 2006
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1 - 18Molly Ringwald, OK Go October 11, 2006
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1 - 19Wanda Sykes, Goran Visnjic, Ruben Studdard October 12, 2006
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1 - 20Peter Gallagher, Nathan Burton, Tyler James Williams October 13, 2006
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1 - 21
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1 - 22Cheyenne Kimball, Laura Linney, Ricardo Antonio Chavira October 17, 2006
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1 - 23Merv Griffin, Kim Raver, Author Jennifer Egan October 18, 2006
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1 - 24Rob Morrow, Rebecca Cole, Anne Heche, Joshua Bell October 19, 2006
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1 - 25
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1 - 26
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1 - 27Jamie Lee Curtis, The Mystic Pixies, Amy Smart, Taylor Swift October 24, 2006
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1 - 28Lauren Holly, Ruben Studdard, Daniel Dae Kim October 25, 2006
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1 - 29
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1 - 30James Denton, Yahoo 9's Maria Sansone, Angela Kinsey, JoJo October 27, 2006
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1 - 31Steven Weber, Audra McDonald October 30, 2006
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1 - 32Neil Patrick Harris, Kevin Federline October 31, 2006
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1 - 33Jamie Kennedy, Jeffrey Sebelia, Meat Loaf, Card Thrower Rick Smith November 01, 2006
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1 - 34Clay Aiken, Tysonia Tschinga "Real Life" Dancing with the Stars November 02, 2006
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1 - 35
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1 - 36
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1 - 37Mark Harmon, Hip Hop Champions, Constance Zimmer, Melora Hardin November 07, 2006
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1 - 38Kevin Nealon, Antonio Sabato Jr. November 08, 2006
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1 - 39Bob Saget, sex educator Sue Johanson November 09, 2006
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1 - 40
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1 - 41Cheryl Hines, Tim Gunn, Thanksgiving Dog Adoption Fashion Show November 13, 2006
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1 - 42David Hyde Pierce, Linda Cardellini, Taylor Ware November 14, 2006
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1 - 43Patricia Arquette, Champion Pirouette Dancer, Daily Candy Trends November 15, 2006
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1 - 44Dax Shepard, Tom Arnold, Kimberley Locke November 16, 2006
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1 - 45Reba McEntire, Patrick Wilson, RBD November 17, 2006
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1 - 46Tom Bergeron, Trista and Ryan, Benji Schwimmer, Rupert Boneham November 20, 2006
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1 - 47Sharon Stone, Scott Foley, Rusty Schwimmer, Paz Vega, Danny Seo November 21, 2006
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1 - 48
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1 - 49Camryn Manheim, Phil Pfister, James Lesure, Author Karen Rizzo November 24, 2006
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1 - 50
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1 - 51David Boreanaz, Julianne Nicholson, Bianca Ryan November 28, 2006
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1 - 52
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1 - 53Tracy Morgan, Melissa Peterman, Jarod Miller, Eric Stromer November 30, 2006
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1 - 54Carrie Fisher, Paul Rodriguez, Nadine Velazquez December 01, 2006
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1 - 55Rosanna Arquette, Tom Green, Adrian Pasdar December 04, 2006
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1 - 56Marla Sokoloff, Taylor Hicks, "Campus Ladies" December 05, 2006
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1 - 57Phyllis Diller December 06, 2006
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1 - 58Carson Kressley, Beau Bridges, Amy Sedaris December 07, 2006
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1 - 59Wendie Malick, Janice Dickinson December 08, 2006
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1 - 60John Stamos, Brenda Strong, Cris Judd, Tyrese December 11, 2006
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1 - 61
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1 - 62Jeffrey Tambor, Tisha Campbell, designer Mark Montano, Hall & Oates December 13, 2006
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1 - 63Shawn and Marlon Wayans, Taylor Hicks December 14, 2006
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1 - 64Oded Fehr, Rob Morrow, Rhea Perlman, Sarah Rush December 15, 2006
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1 - 65Howie Mandel, Jennie Garth, Ahmet Zappa, psychic medium Lisa Williams December 18, 2006
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1 - 66Jane Seymour, David Conrad, Ken Davitian, Joshua Radin December 19, 2006
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1 - 67Alfre Woodard, Milo Ventimiglia, Fantasia Barrino December 20, 2006
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1 - 68Billy Ray Cyrus, Richard Simmons, authors of "Party Confidential" December 21, 2006
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1 - 69
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1 - 70Emily Procter, Tichina Arnold, Goo Goo Dolls January 08, 2007
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1 - 71Natalie Cole, Craig Bierko, Dave Annable, Blaine Zuckerman January 09, 2007
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1 - 72
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1 - 73Patricia Heaton, Cheryl Hines, Debra Messing, Christine Taylor January 16, 2007
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1 - 74Josh Duhamel, Jamie Kennedy, George Lopez, Mario Lopez January 17, 2007
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1 - 75
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1 - 76Chandra Wilson, Jesse Bradford, Clay Aiken January 24, 2007
Overview
Two-time Emmy Award-winner Megan Mullally, coming off eight seasons as wisecracking socialite Karen Walker on NBC's "Will & Grace," moves into the driver's seat as host for this daytime talk show. Each episode is an entertaining hour featuring a mix of celebrities, real people, music, and comedy. Megan will interview top celebrities and also introduce the world to guests of all kinds — from quirky characters to funny kids to offbeat experts.
Cast
Self - Host
Self - Music Director / Keyboardist
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